Abstract
Metabolic syndrome (MetS) is a strong risk factor for Coronary Heart Disease (CHD) and type II Diabetes mellitus (DM). The aim of the present study was to determine whether yoga can regress early atherosclerosis in patients with MetS, as measured by carotid intima thickness (cIMT). 100 adult patients of MetS were randomized to yoga and control group and were followed for 1 year. 81% patients completed the study. At the end of 1 year, the yoga group showed a significant regression of cIMT (0.842 ± 0.176 to 0.808 ± 0.204, p<0.001) whereas there was no significant change in cIMT in the control group (0.831 ± 0.171 to 0.834 ± 0.131, p=NS). In addition the yoga group also showed greater reduction in Body Mass Index (BMI), Waist Circumference (WC), LDL cholesterol and Systolic Blood Pressure (SBP). On the basis of this randomized study, we conclude that practice of yoga can regress early atherosclerosis in MetS and has also beneficial effects on several metabolic parameters. The mechanisms of the improvement are not evident from the present study andneed further investigations.
Highlights
Metabolic syndrome (MetS), a clustering of risk factors is highly prevalent throughout the world especially in South Asians [1] and is a strong risk factor for Coronary Heart Disease (CHD) and type 2 Diabetes Mellitus (DM) [1,2,3]
There was a significant reduction in Body Mass Index (BMI), Waist Circumference (WC), LDL, Tg, FBS, HbA1C, Systolic Blood Pressure (SBP) and DBP and increase in HDL in both the groups (Table 2), but when compared with control, yoga group had a significant greater decrease in BMI, WC, LDL and SBP levels and increase in HDL
Paul-Labrador et al [15] reported that 16 weeks of practice of transcendental meditation (TM) led to a significant reduction in insulin resistance which is considered as the basisof metabolic syndrome
Summary
Metabolic syndrome (MetS), a clustering of risk factors is highly prevalent throughout the world especially in South Asians [1] and is a strong risk factor for Coronary Heart Disease (CHD) and type 2 Diabetes Mellitus (DM) [1,2,3]. The definition of metabolic syndrome as modified for the south Asians is by the following criteria [2]. 1. Central Obesity (defined as waist circumference ≥ 90 cms for males and ≥ 80 cms forfemales). 2. Raised triglyceride level ≥ 150 mg/dL. 3. Reduced HDL
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