Abstract
Hypertrophy and fibrosis represent structural changes in the myocardium which occur in heart failure and decrease the ability of the heart to contract. We have previously demonstrated that reduction of load by LVAD support induces a decrease in cardiac interstitial fibrosis as well as myocyte size. We also have reported that cardiac mast cells increase in heart failure and that a secondary increase occurs post LVAD. The secondary increase, however, is composed of primarily chymase negative mast cells and these mast cells show an altered (reduced) bFGF content.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
