Abstract

Abstract Aim: This study aims to investigate whether there is a substantial difference between single- and multiple-visit root canal treatment (RCT) in regard to the incidence and intensity of postendodontic pain and flare-up. Materials and Methods: The following databases were searched and evaluated “Cochrane Database of Systematic Reviews, Web of Science, PubMed, and Scopus databases” for studies published from January 2000 to August 2021. The articles were chosen using the PRISMA protocol. The review includes 22 articles. Results: The other studies assessed either the incidence or the intensity, while three studies compared both. The majority of studies irrigated with sodium hypochlorite and used both hand-driven and rotary equipment. Thirteen trials made use of an intracanal medicament. Conclusion: The systematic review demonstrated that there was no significant difference in the incidence or the intensity of the pain as measured between single-visit RCT and multiple-visit RCT. The incidence of postendodontic pain or a flare-up is not independently determined by the number of visits required for root canal therapy.

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