Objective To evaluate systematic reviews or Meta-analyses related to ventilator-associated pneumonia (VAP) in closed suction system or open suction system. Methods CNKI, CBM, Cochrane Library, Web of Science, MEDLIN and Embase databases were searched for systematic reviews or meta-analyses in closed suction system and open suction system. Two reviewers independently evaluated the articles, and then extracted the data. QQAQ evaluation sheet was used to assess and cross-check reporting characteristics and methodological quality of included literature respectively, and divergence would be resolved by discussion. Results Nine systematic reviews or Meta-analysis were included, which involved three aspects: incidence rate of VAP, airway colonization bacteria and the duration of mechanical ventilation. Conclusions This revaluation of systemic evaluation provides high-quality evidence resources and provides reliable evidence support for the development of clinical practice. Key words: Meta-analysis; Systematic review; Closed suction system; Ventilator-associated pneumonia

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