Retrospective study on nasopharyngeal cancer (RENOCS): outcome management of in-hospital patients

Abstract

Link of Video Abstract: https://youtu.be/J6ZC8xzJB8MBackground: Nasopharyngeal carcinoma (NPC) is distinct from other head and neck cancers in terms of epidemiology, clinical presentation, biological markers, carcinogenic risk factors, and prognostic factors. However, there is only a small amount of information available on NPC in Indonesia, where the recorded mean prevalence is 6.2/100,000 and there are 13,000 new cases reported annually. Numerous treatments are used, and it's important to pinpoint the risk factor that contributes to a poor prognosis. The aim of this study is to look at the outcomes of nasopharyngeal cancer patients who were hospitalized at a referral hospital based on their characteristics and laboratory results. Methods: Data from medical records were analyzed to conduct a retrospective study. Up to 785 patients who were hospitalized at a single referral hospital from 2018 to 2022 and received a nasopharyngeal cancer diagnosis were included. Data were statistically and descriptively analyzed. Results: Chronic kidney disease, education level, and tumor, node, metastasis (TNM) classification was associated with patient outcomes (p < 0.05). The results of the multivariate analysis showed that there were significant differences in the variables of chronic kidney disease and pre-treatment albumin levels. Therefore, people with nasopharyngeal cancer who have chronic kidney disease have a 12,151 chance of mortality. Conclusion: In Indonesia, there is a critical need for efforts to identify NPC as early as possible. These should include public education to increase awareness of the comorbidity status, especially chronic kidney disease to prevent poor outcomes.