Abstract
BackgroundThis study was performed to evaluate their 5-year survival rates and identify the factors affecting the prognosis of oral cancer patients who had undergone surgical treatment only.MethodsAmong 130 patients who were diagnosed with malignant tumor of oral, maxillofacial, and surgical treated in the Department of Oral and Maxillofacial Surgery at Chonnam National University Hospital within a period from January 2000 to December 2010, for 11 years, 84 patients were investigated who were followed up for more than 5 years after radical surgery; oral cancer is primary and received only surgical treatment. The survival rate according to gender, age, type and site of cancer, TNM stage, cervical lymph node metastasis and its stage, recurrence or metastasis, time of recurrence and metastasis, and differentiation were investigated and analyzed.ResultsOverall, 5-year survival rate in patients who received only surgical treatment was 81.2 %, and disease-specific 5-year survival rate was 83.1 %. The disease-specific 5-year survival rate based on TNM stage, metastasis of cervical lymph node, N stage, and presence of recurrence/metastasis was a significant difference (p < 0.05). The disease-specific 5-year survival rate based on sex, age, type of tumor, primary site, and differentiation was not a significant difference (p > 0.05).ConclusionsThese results suggest that good survival rate can be obtained with surgical treatment only, and stage of oral cancer, cervical lymph node metastasis and stage, recurrence or metastasis, time of recurrence, and metastasis have a significant effect on survival rate in oral cancer patients.
Highlights
This study was performed to evaluate their 5-year survival rates and identify the factors affecting the prognosis of oral cancer patients who had undergone surgical treatment only
Prognosis according to gender and age Oral cancer patients receiving surgery treatment were 58 male and 26 female, and the rate was higher 2.3 times in men, and overall, 5-year survival rate was 81.2 %
The disease-specific 5-year survival rate according to gender showed no significant difference, and results of log rank test showed that sex does not affect prognosis (Table 1)
Summary
This study was performed to evaluate their 5-year survival rates and identify the factors affecting the prognosis of oral cancer patients who had undergone surgical treatment only. For the treatment of oral cancer, it is still controversial, but usually, surgical treatment is preferred in the initial oral cancer and the cases of progressed oral cancer like cervical lymph node metastasis or extracapsular spread have been performed with surgical treatment along with combination therapy and radiation therapy [1]. It has emerged as an important factor of treatment decisions, quality of life in addition to the possibility of oral cancer recovery [2]. Chemotherapy is applied to advanced stage, extracapsular spread, recurrence or metastasis, and the case of palliative therapy
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