Retrospective study for correlation of fetal middle cerebral artery PSV and fetal anemia using newborn hemoglobin and blood indices

Abstract

To establish relation between fetal MCA’s PSV in 3rd trimester and fetal anemia as non-invasive method. The study was done retrospectively, including 40 pregnant women who had raised PSV of MCA (Multiple of Median(MoM) >1.5) blood flow in third trimester and was correlated with the new born’s Hemoglobin and Blood indices (MCV and MCH). Forty fetuses who had MCA’s PSV more than 1.5 MoM(coming out to be around 66.50 ± 12.35 cm/seconds), after delivery, blood samples of these 40 neonate were taken, of which 37 were anemic based on hemoglobin and blood indices using reference range from study done by kumar et al8. Sensitivity was 92.5% and specificity around 88 %. Doppler spectral analysis of PSV of MCA is very reliable for predicting fetal anemia. MoM of PSV of Fetal MCA correlates very well with MoM of Neonatal Hemoglobin . Thus, fetal MCA’s PSV is very potential to replace invasive method for diagnosis of fetal anemia.