Abstract

Microfocused ultrasound (MFU) is an effective means for tightening and lifting lax facial and neck skin. To evaluate the safety and efficacy of MFU with visualization (MFU-V) for noninvasive treatment of facial and neck skin laxity 180days after treatment and determine what lifestyle factors affect treatment outcomes. Healthy women (N=48) previously treated with MFU-V on the face and upper neck were enrolled. Depending on when MFU-V treatment occurred, subjects completed 90- or 180-day follow-up visits or both. Digital images of each subject were obtained before treatment and at follow-up visits. Data were obtained at 90 (N=16) and 180days (N=45), and physician Global Aesthetic Improvement Scale (GAIS) scores demonstrated that 81.3% and 77.7% patients achieved improvement, respectively. At 90 and 180days, subject GAIS scores showed 75% and 77.8% of subjects perceived improvement, respectively. At 180days, blinded reviewer assessments indicated that 67% of subjects showed improvement in appearance. There was no association between improvement and age, Fitzpatrick skin type, alcohol intake, or major illness. One minor adverse event was reported. Although the data obtained at 90days must be interpreted cautiously because of the smaller number of patients, subjects achieved significant lifting and tightening of facial and neck skin up to 180days after one MFU treatment.

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