Retrospective comparative clinical study for silk mat application into extraction socket

Ju-Won Kim,Jwa-Young Kim,You-Young Jo,Byoung-Eun Yang,Ji-Hyeon Oh,Seong-Gon Kim

doi:10.1186/s40902-019-0199-z

Abstract

BackgroundSilk mats have been approved for clinical trials by the Korean Food and Drug Administration as membranes for guided tissue regeneration (GTR). In this study, silk mat application was compared to high-density polytetrafluoroethylene (dPTFE) membrane application or no membrane group.MethodsTo compare the silk mat group to the dPTFE group or the no membrane group, a retrospective sample collection was conducted. Bony defects were measured at the time of extraction (T0) and then at 3 months (T1) and 6 months after extraction (T2) on a digital panoramic view. Bone gain (BG) was calculated by subtracting from the bony defect at T0 to the bony defect at each follow-up.ResultsThe BG at T2 was 2.44 ± 2.49 mm, 4.18 ± 1.80 mm, and 4.24 ± 2.05 mm in the no membrane group, silk mat group, and dPTFE group, respectively. Both membrane groups had significantly higher BG than BG in the no membrane group at T2 (P < 0.05).ConclusionsBoth membrane groups showed higher BG than the no membrane group.

Highlights

Silk mats have been approved for clinical trials by the Korean Food and Drug Administration as membranes for guided tissue regeneration (GTR)
There was no significant difference in the size of the bony defect between groups at T0 (P > 0.05)
Silk mat has been widely studied as a membrane for guided tissue regeneration (GTR) [13, 15]

Summary

Introduction

Silk mats have been approved for clinical trials by the Korean Food and Drug Administration as membranes for guided tissue regeneration (GTR). Silk mat application was compared to high-density polytetrafluoroethylene (dPTFE) membrane application or no membrane group. Deep pocket formation adjacent to the second molar is a late-onset complication. This periodontal defect is frequent in cases of deeply impacted lower third molar surgery [4, 5]. The systemic condition of the patient may influence this complication [6, 7], the local environment in the impacted teeth is the main etiologic factor [5]. This impaired bone defect is associated with a critical-sized bone defect and may require treatment via graft [8, 9]

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