Abstract
HTLV-I –associated tropical spastic paraparesis (TSP) and HTLV-I associated myelopathy (HAM) is an endemic disease in Carribean Island. Bladder-sphincter dysfunctions are almost present. Functional disablement is major. Few studies are devoted to urinary disablement, responsible for urologic complications, that gives one of the elements of the severity prognosis of the disease. The objectives of the study are first to describe clinic and urodynamic characteristics of voiding disorders in Martiniquan population, secondly evaluate if there is a relationship between motor and urinary handicap, and thirdly evaluate prognosis factors of urologic complications.
Highlights
HTLV-I –associated tropical spastic paraparesis (TSP) and HTLV-I associated myelopathy (HAM) is an endemic disease in Carribean Island
Retrospective clinic and urodynamic study in the Neurogenic Bladder Dysfunction caused by Human T Cell Lymphotrophic Virus Type 1 Associated Myelopathy / Tropical spastic paraparesis (HAM/TSP)
Detrusor sphincter dysynergia was found in 78% of the cases, post-void residual in 58% of cases. 65% of the patients present at least one urologic complication but there was no correlation with motor enablement (p=0.3097), neither urodynamic study (p=0.432 for detrusor overactivity, p = 0.107 for detrusor underactivity, p=0.058 for high urethral activity, p= 0.893 for detrusor sphincter dysynergia, p=0.850 for post-void residual volume), neither with evolution duration of HAM/TSP (p=0.348)
Summary
HTLV-I –associated tropical spastic paraparesis (TSP) and HTLV-I associated myelopathy (HAM) is an endemic disease in Carribean Island. Few studies are devoted to urinary disablement, responsible for urologic complications, that gives one of the elements of the severity prognosis of the disease. The objectives of the study are first to describe clinic and urodynamic characteristics of voiding disorders in Martiniquan population, secondly evaluate if there is a relationship between motor and urinary handicap, and thirdly evaluate prognosis factors of urologic complications
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