Retrospective analysis of the bone marrow received at a tertiary care hospital- A study of 160 cases

Abstract

Introduction: Bone marrow examination becomes a crucial test in diagnosis of both hematological and non hematological malignancies, when the routine peripheral blood and other laboratory tests are not conclusive of a diagnosis. Aim: The aim of this study was to find the indications of bone marrow and to assess the diagnostic value. Materials and Methods: A total of 160 cases were analyzed retrospectively from January 2016 to December 2017. All the bone marrows received at the laboratory were included in the study. Result: The youngest patient was 2 years old and the oldest 80 years. Amongst 160 cases 89 (55.62%) were male and 71 (44.37%) were female. M: F ratio is 1.25:1. Leucocytosis was the most common indication of bone marrow examination followed by bicytopenia and pancytopenia. Acute leukemia was the most frequented diagnosis (13.12%) followed by idiopathic thrombocytopenic purpura (11.25%), myeloproliferative diseases (8.12%) and myeloma (8.12%). Few of the rare diagnosis included hemophagocytic syndrome, hypersplenism and aplastic anemia. Conclusion: The study concludes the bone marrow examination is crucial and important in reaching a diagnosis in most of the cryptic cases of cytopenias and unexplained leucocytosis. Keywords: Bone marrow examination, Cytopenia, Leukemia