Retrospective Analysis of Metabolic Syndrome, Risk Factors and Therapeutic Approach: A Study among Patients of Malwa Region

Abstract

Metabolic syndrome is illustrated by the concur of several cardiovascular risk factors including insulin resistance, central obesity, visceral adiposity, atherogenic dyslipidemia and hypertension. The proposed study was conducted on 133 patients within the course of 6 months from various region of Malwa. The data was collected using patients’ diagnostic reports, prescriptions and medical history and was separately studied using Microsoft excel 2009 spread sheets. A total of 133 patients were enrolled for this study. 46.7% were already suffering from Metabolic disorder remaining 53.3% patients were at risk of it. Group II patients were detected with high level of triglyceride, uncontrolled diabetes, hypothyroidism besides stage II hypertension, ischemic heart disease and angina pectoris. In Group I T2DM, hyperthyroidism, hypertension besides acute myocardial infraction and Angina was identified. Whereas in Group III patients, angina pectoris was dormant in addition to cardiovascular diseases, ischemic heart disease and acute myocardial infraction. Antacids, antidiabetic, antihypertensive, diuretics, vitamins, statins, glucocorticoids, non-steroidal anti-inflammatory drugs were preferably prescribed medications. Certain class of medication were found to influence risk of metabolic syndrome due to their Adverse drug reaction. Delayed identification and certain Adverse drug reaction were identified by reviewing medication grids. Multi-fold domain such as genetic, behavioral, lifestyle and clinical factors also contributed in metabolic syndrome. Therefore, health care professionals, pharmacist, patients and caregivers need to collaborate and explore better behavioral, healthy lifestyle and safer medications to avoid the additional complicity and breakthrough of Metabolic syndrome.