Abstract

The most common lesions of the large intestine are polyposis lesions belonging to pre-tumor neoplasms, which, in case of untimely diagnosis and inadequate treatment, may transform into colorectal cancer. Objective: to study pathomorphological variants of localization of large intestine polyposis lesions. The work deals with the analysis of the advisory conclusions of the results of pathoanatomical investigations of polyposis lesions of the large intestine at the Department of Pathological Anatomy and Forensic Medicine, Danylo Halytsky Lviv National Medical University, for the period of 2005-2016. The rectum and sigmoid were found to be the most common localization of polyposis lesions. The prevalence of polyposis lesions in men was evidenced to be reliably (p <0.01) higher than that of women. In men, the first place in the frequency of lesions is the rectum, in women – sigmoid colon. The overwhelming majority (3/4) of simultaneous lesions of two parts of the large intestine were observed in men. The most common lesions were associations with sigmoid colon: sigmoid colon + ascending (32.14 ± 8.83%), sigmoid colon + rectum (21.43 ± 7.75%), sigmoid colon + descending (14.29 ± 6.61%). The results of this study are perspective in terms of practical application. They can be the basis for diagnosis and prediction of occurrence of polyposis lesions in future.

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