Retrospective analysis of 26 cases of inverted nasal papillomas

Ana Maria Almeida De Sousa,Alcioni Boldrini Vicenti,José Speck Filho,Michel Burihan Cahali

doi:10.1590/s1808-86942012000100004

Abstract

Inverted papilloma (IP) comprises 0.5-4% of benign nasal tumors. The importance is shown by local aggressiveness, a high recurrence rate and the possibility of malignant transformation. The treatment is controversial, but endoscopic approaches tends to be the choice today. AimTo describe clinical, epidemiological and treatment of IP cases in a tertiary hospital. MethodsRetrospective study consisting of chart reviews of 26 patients diagnosed with IP; evaluation of tumor location, clinical staging, follow up, tumor recurrence, malignancy, type of surgery and postoperative complications. ResultsThere were 13 men and 13 women, the mean age was 57.8 years. The mean follow up time was 29.4 months; the recurrence rate was 7.6%. There was a preponderance of T3 and T4 tumors and a 3.8% malignancy rate. All patients underwent surgical treatment, mostly endonasal endoscopic surgery. ConclusionIP is an uncommon nasal tumor that originates mainly in the lateral nasal wall, but it also affects the paranasal sinuses. Advances in endoscopic surgery are gaining room due to lower invasiveness and success rates similar to traditional external techniques for completely resecting the tumor. There is a lower recurrence rate, and endoscopy a definitive treatment for malignancy cases in this study.

Highlights

The inverted papilloma is a benign epithelial tumor of the nasal mucosa and paranasal sinuses in which epithelium invaginates towards the stroma[1]
The inverted papilloma comprises about 0.5% to 4% of primary nasal tumors, and it is clinically significant because it is locally aggressive and its recurrence rates range from 5% to 30%
The review consisted of 27 registries of patients with a diagnosis of inverted papilloma confirmed by pathology

Summary

Introduction

The inverted papilloma is a benign epithelial tumor of the nasal mucosa and paranasal sinuses in which epithelium invaginates towards the stroma[1]. It originates mostly on the lateral nasal wall or within the maxillary sinus. The inverted papilloma comprises about 0.5% to 4% of primary nasal tumors, and it is clinically significant because it is locally aggressive and its recurrence rates range from 5% to 30% This tumor appears to undergo malignant transformation into squamous cell carcinoma in 5% to 15% cases[4,5,6,7,8]. It may cause thinning and even erosion of underlying bone, and it may extend into the orbit or intracranial cavity[8]

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