Abstract
Interferon-γ-inducible protein 10(IP-10), also known as chemokine(C-X-C motif) ligand 10(CXCL10), belongs to the CXC subfamily. IP-10 exerts its function by binding to chemokine (C-X-C motif) receptor 3 or Toll-like receptor 4. IP-10 plays an important role in the occurrence and development of autoimmune diseases. The expression of IP-10 in blood and body fluid is closely associated with the activity of autoimmune disease. IP-10 is expected to become a potential new marker and possess a significant application value in early screening, condition monitoring and therapeutic evaluation of autoimmune diseases.(Chin J Lab Med, 2015, 38: 805-808) Key words: Autoimmune diseases; Chemokine CXCL10; Biological markers
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