Abstract

BacgroundLaparoendoscopic single-site surgery (LESS) has been developed in an attempt to further reduce the morbidity and scarring associated with laparoscopic surgery. In patients in whom there are indications to perform a laparoscopic renal biopsy, LESS surgery is a valid alternative to mini invasive surgery and is becoming more common. We report our experience on 14 renal biopsy procedures performed in a retroperitoneal LESS.MethodsLESS renal biopsy was performed in 14 patients 18 to 80 years old (mean age 58.3 years) during a 36 month period. All procedures were performed by a single operator. The patient was in a standard flank position. The procedure was performed using a 2.5 cm, single incision via a retroperitoneal access at the Petit’s triangle. A 5 mm biopsy forceps was used to collect the specimen under direct vision, and haemostasis was obtained with an Argon beam probe and the application of oxidized regenerated cellulose gauze.ResultsBiopsy was performed successfully in all cases. Mean operative time was 52.64 min, blood loss was minimal, and the hospital stay ranged from 12 to 24 hours. None of the patients required narcotics or additional analgesia in the postoperative period. No postoperative complications occurred.ConclusionsThe LESS technique is safe, reliable (100% success), easy to learn, and offers subjective cosmetic benefits to the patient. Minimal hospitalization requirement following retroperitoneal LESS biopsy is an additional timely advantage over laparoscopic renal biopsy. We think that with the right indications (marked obesity, failure of previous percutaneous biopsy attempts, a solitary kidney and coagulopathy) LESS renal biopsy is a good alternative to laparoscopy. Our next step will be a randomized prospective study of LESS compared with laparoscopy for renal biopsy to support our findings.

Highlights

  • Histological evaluation of renal parenchyma is often essential in cases of several renal diseases with unexplained azotemia, proteinuria, hematuria, or systemic disease

  • We present our preliminary experience with retroperitoneal Laparoendoscopic single-site surgery (LESS) in a series of 14 subjects who required renal biopsy

  • All 14 LESS biopsy procedures were successfully performed with sufficient tissue obtained for histopatological diagnosis in all cases (Table 1)

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Summary

Introduction

Histological evaluation of renal parenchyma is often essential in cases of several renal diseases with unexplained azotemia, proteinuria, hematuria, or systemic disease. Pathological diagnosis often provides useful information in determining the prognosis and guiding the treatment. Ultrasound-guided renal biopsy represents an essential step in the study of renal diseases [1]. The last few decades have transformed the renal biopsy into a safe technique that plays a central role in the nephrological diagnostic approach [2]. As many as 5 to 20% of cases yield inadequate tissue for histopathology diagnosis. Percutaneous kidney biopsy is not without risk. Over complications occurring in up to 13% of the cases, and 6 to 7% of complications were considered major, needing for an intervention such as transfusion of blood product or invasive procedure (radiographic or surgical) [3]

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