Abstract
The clinical features of 19 patients with malignant infiltration of the retroperitoneal tissues are described. These patients usually presented with unexplained uraemia and nonspecific symptoms; only a few had other evidence of malignancy. The diagnosis was resolved only by histological examination of multiple biopsy specimens. Since the prognosis is usually very poor it is essential to distinguish this condition from non-malignant causes of retroperitoneal fibrosis.
Highlights
Summary.-The clinical features of 19 patients with malignant infiltration of the retroperitoneal tissues are described
Retroperitoneal fibrosis may be considered in three groups-idiopathic, The most common presenting symptoms were those due to uraemia, particunon-malignant and malignant
Eight of the 19 patients secondary to a variety of primary tumours were known to have been treated for including breast, stomach, prostate and malignant disease (Table II) and these cervix (Ormond, 1960), reticulum cell sarcoma (Treves, 1958) and Hodgkin's disease (Nitz et al, 1970)
Summary
Summary.-The clinical features of 19 patients with malignant infiltration of the retroperitoneal tissues are described. These patients usually presented with unexplained uraemia and nonspecific symptoms; only a few had other evidence of malignancy. Since the prognosis is usually very poor it is essential to distinguish this condition from non-malignant causes of retroperitoneal fibrosis. One patient was found to have a malignant pleural effusion on physical examination, another proven malignant retroperitoneal fibrosis had an irregular abdominal mass and a in order to characterize the clinical features of a condition in which the third (with giant follicular lymphoma) had palpable axillary and supraclavicular.
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