Retroperitoneal fibrosis, 1 case reported and analysis of 106 cases in China

Abstract

Objectives To analysis the clinical features of retroperitoneal fibrosis (RPF) in China, and to investigate the early diagnostic signs of RPF. Methods We retrospectively analyzed the clinical data of 107 RPF patients ,including lease in our hospital and 106 cases reported in other hospitals in China. Results The inci-dence of RPF in male was higher than that in female (2.9 : 1), the age was from 20 to 84 years old, averaged (50. 9 ±10.3). The initial symptoms of RPF: abdominal pain, notalgia were found in 66 patients (61.7%), urinary tract obstruction 19 patients(17.8%). Physical signs: swollen leg, abdominal mass, fever, ascites were found in 13 patients(12. 1%), 9 patients(8.4%), 2 patients(1.9%), 1 patient(0.94%), respectively. Imaging examination is very important: there were 78 cases(72.9%) of renal hydrocele or upper ureter pathological found by B mode ul-trasonography, IVP or CT; 79 cases (73.8%) of abdominal mass, organ adhenaiou were found by CT and MRI. Curative effect was relation with developmental phase and degree of RPF. Use of glucocorticoid was essential in in-flammation; When fibrosis was formed and tanned to obstruction, it should be operated in time. Conclusions The incidence of RPF was higher in male than in female, mainly in middle -aged. The initial syrup toms of RPF are not specific, including abdominal pain, antalgia , waist pain, urinary tract obstruction,leg edema, abdominal mass, Image examination is very important in diagnosis and differential diagnosis. The direct of Glucocorticoid and (or) im-munosuppreasant is good in the early stage. While,in the late stage, surgery and(or) intervention is needed to treat organ oppression and obstruction. Besides, Glucocorticoid is still needed to reduce the relapse rate. Key words: Retroporitoneal Fibrosis