Abstract
Some proteins like acid hydrolase receptor, hetero trimeric G protein, EGFR, processing peptidase as well as toxin like Shiga toxin, ricin and lipid trafficks through various intermediate stations while travelling from endosomes to trans Golgi network/Golgi ie 'Retrograde' transport after being internalised. Here the critical molecular events in the retrograde pathway along with the factors involved are summarised. Then the importance and implication in various cellular processes are discussed. Lastly, I conclude about the future perspective and in what way we can exploit the process for applied research.
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