Retrograde ejaculation and sexual dysfunction in men with diabetes mellitus

Abstract

ObjectiveRetrograde ejaculation (RE) may be caused by Diabetes mellitus. The frequency of RE in a population of men with diabetes mellitus was evaluated.DesignClinical, prospective case-control study blindly performed.Materials and MethodsDiabetic men and controls were recruited from a unique case-control Diabetes Biobank consisting of 6000 diabetic patients and 6000 controls, males and females 26-74 years of age. Registered males within the age range of 30-55 years were asked to participate in the present sub project.Participants filled out a 15-item measurement scale for male sexual function representing an International Index of Erectile Function (IIEF-15). Furthermore, participants delivered ejaculates and post-ejaculatory urine samples for immediate examination. Participants were asked to urinate immediately before ejaculation. Concentration, motility, and total number of sperm were determined. Data on RE and sexual dysfunction was related to data in the Diabetes Biobank: lifestyle factors, medical sequelae and, fat percent, and blood pressure as well as hormone levels.ResultsThe study group was limited due to gender and age. Additionally, a substantial number of men declined arguing they “had the number of children they wanted” or “knew they had diabetes and RE”. In total 45 persons were included, hereof 27 diabetic men. Nine of the diabetic participants showed RE, while none among 18 controls did (P<0.05). Although not statistically significant, diabetic men with RE had been diabetic longer than the men without RE. Diabetic men – and particularly diabetic men with RE - scored their sexual life as significantly poorer than did the controls.ConclusionRE occurs with a significantly higher frequency in men with diabetes mellitus, and these men suffer from sexual dysfunction. ObjectiveRetrograde ejaculation (RE) may be caused by Diabetes mellitus. The frequency of RE in a population of men with diabetes mellitus was evaluated. Retrograde ejaculation (RE) may be caused by Diabetes mellitus. The frequency of RE in a population of men with diabetes mellitus was evaluated. DesignClinical, prospective case-control study blindly performed. Clinical, prospective case-control study blindly performed. Materials and MethodsDiabetic men and controls were recruited from a unique case-control Diabetes Biobank consisting of 6000 diabetic patients and 6000 controls, males and females 26-74 years of age. Registered males within the age range of 30-55 years were asked to participate in the present sub project.Participants filled out a 15-item measurement scale for male sexual function representing an International Index of Erectile Function (IIEF-15). Furthermore, participants delivered ejaculates and post-ejaculatory urine samples for immediate examination. Participants were asked to urinate immediately before ejaculation. Concentration, motility, and total number of sperm were determined. Data on RE and sexual dysfunction was related to data in the Diabetes Biobank: lifestyle factors, medical sequelae and, fat percent, and blood pressure as well as hormone levels. Diabetic men and controls were recruited from a unique case-control Diabetes Biobank consisting of 6000 diabetic patients and 6000 controls, males and females 26-74 years of age. Registered males within the age range of 30-55 years were asked to participate in the present sub project. Participants filled out a 15-item measurement scale for male sexual function representing an International Index of Erectile Function (IIEF-15). Furthermore, participants delivered ejaculates and post-ejaculatory urine samples for immediate examination. Participants were asked to urinate immediately before ejaculation. Concentration, motility, and total number of sperm were determined. Data on RE and sexual dysfunction was related to data in the Diabetes Biobank: lifestyle factors, medical sequelae and, fat percent, and blood pressure as well as hormone levels. ResultsThe study group was limited due to gender and age. Additionally, a substantial number of men declined arguing they “had the number of children they wanted” or “knew they had diabetes and RE”. In total 45 persons were included, hereof 27 diabetic men. Nine of the diabetic participants showed RE, while none among 18 controls did (P<0.05). Although not statistically significant, diabetic men with RE had been diabetic longer than the men without RE. Diabetic men – and particularly diabetic men with RE - scored their sexual life as significantly poorer than did the controls. The study group was limited due to gender and age. Additionally, a substantial number of men declined arguing they “had the number of children they wanted” or “knew they had diabetes and RE”. In total 45 persons were included, hereof 27 diabetic men. Nine of the diabetic participants showed RE, while none among 18 controls did (P<0.05). Although not statistically significant, diabetic men with RE had been diabetic longer than the men without RE. Diabetic men – and particularly diabetic men with RE - scored their sexual life as significantly poorer than did the controls. ConclusionRE occurs with a significantly higher frequency in men with diabetes mellitus, and these men suffer from sexual dysfunction. RE occurs with a significantly higher frequency in men with diabetes mellitus, and these men suffer from sexual dysfunction.