Retraction of: Ablation of Adenosine Monophosphate-Activated Protein Kinase α1 in Vascular Smooth Muscle Cells Promotes Diet-Induced Atherosclerotic Calcification In Vivo.

Abstract

The following Circulation Research article is being retracted: Cai Z, Ding Y, Zhang M, Lu Q, Wu S, Zhu H, Song P, Zou MH. Ablation of Adenosine Monophosphate-Activated Protein Kinase α1 in Vascular Smooth Muscle Cells Promotes Diet-Induced Atherosclerotic Calcification In Vivo . Circ Res. 2016;119:422–433. doi: 10.1161/CIRCRESAHA.116.308301. The editors received a request from the University of Oklahoma Health Sciences Center to retract the above referenced article due to data irregularities and image reuse in Figure 3 that affect the results and conclusions reported in the manuscript. Specifically, the following irregularities were found: In Figure 3D, the top left panel immunohistochemistry image labeled “ApoE – / – with “Runx2” staining was reused in Figure 4A, bottom left panel immunohistochemistry image labeled “ApoE – / – /AMPKα1 f/f ” with “Runx2” staining. The editors are retracting this article in agreement with the University of Oklahoma. The authors do not agree to the retraction.