Abstract
During 2014-2017, we isolated a novel orthobunyavirus from broiler chickens with severe kidney lesions in the state of Kedah, Malaysia; we named the virus Kedah fatal kidney syndrome virus (KFKSV). Affected chickens became listless and diarrheic before dying suddenly. Necropsies detected pale and swollen kidneys with signs of gout, enlarged and fragile livers, and pale hearts. Experimental infection of broiler chickens with KFKSV reproduced the disease and pathologic conditions observed in the field, fulfilling the Koch's postulates. Gene sequencing indicated high nucleotide identities between KFKSV isolates (99%) and moderate nucleotide identities with the orthobunyavirus Umbre virus in the large (78%), medium (77%), and small (86%) genomic segments. KFKSV may be pathogenic for other host species, including humans.
Highlights
We assert that research was performed in good faith, that all the experimental data contained in the article are well founded and scientifically valid, and that there was no scientific misconduct
We subsequently were made aware of further information about the epidemiologic and clinical observations made locally in Malaysia, which brings into question the geographic location where the noted virus originated
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Summary
Retraction: Novel Orthobunyavirus Causing Severe Kidney Disease in Broiler Chickens, Malaysia, 2014–2017 Author affiliations: Ceva-Phylaxia Veterinary Biologicals Co. Ltd., Budapest, Hungary
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