Retraction Notice to: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy Phenotype

Abstract

(Cell Metabolism 8, 249–256; September 3, 2008) This article reports that PGC-1α improves mitochondrial myopathy and that its overexpression can compensate for an OXPHOS defect. Following an investigation of the first author, Dr. Wenz, by the University of Cologne, Germany, the university came to the conclusion that scientific misconduct was proven with respect to the above paper. Specifically, blot duplications were identified in Figures S3, S4, and S5. Given that the scientific integrity of the study has been compromised, we see the retraction of the paper as the best corrective action and sincerely apologize to the scientific community. RETRACTED: Activation of the PPAR/PGC-1α Pathway Prevents a Bioenergetic Deficit and Effectively Improves a Mitochondrial Myopathy PhenotypeWenz et al.Cell MetabolismSeptember 03, 2008In BriefThis article has been retracted: please see Elsevier Policy on Article Withdrawal ( http://www.elsevier.com/locate/withdrawalpolicy ). This article has been retracted at the request of the authors. This article reports that PGC-1α improves mitochondrial myopathy and that its overexpression can compensate for an OXPHOS defect. Following an investigation of the first author, Dr. Wenz, by the University of Cologne, Germany, the university came to the conclusion that scientific misconduct was proven with respect to the above paper. Full-Text PDF Open Archive