Retraction: Hepatitis C Virus Core Protein Down-Regulates p21Waf1/Cip1 and Inhibits Curcumin-Induced Apoptosis through MicroRNA-345 Targeting in Human Hepatoma Cells.

The Plos One Editors

doi:10.1371/journal.pone.0235375

Abstract

Retraction: Hepatitis C Virus Core Protein Down-Regulates p21Waf1/Cip1 and Inhibits Curcumin-Induced Apoptosis through MicroRNA-345 Targeting in Human Hepatoma Cells.

Highlights

The PLOS ONE Editors re-reviewed the concerns about the 4th and 5th FACS panels in Fig 3C, which were discussed previously in [2]
The β-actin panels in Fig 2C and S4 Fig appear similar, they represent different experiments. This image issue has implications for the quantitative data reported for the corresponding western blot panels
The authors provided results from an independent replicate for each experiment and noted that an error may have been made in preparing S4 Fig, but they did not provide uncropped images of the original raw blots to support the published results

Summary

Introduction

The PLOS ONE Editors re-reviewed the concerns about the 4th and 5th FACS panels in Fig 3C, which were discussed previously in [2]. The β-actin panels in Fig 2C and S4 Fig appear similar, they represent different experiments. This image issue has implications for the quantitative data reported for the corresponding western blot panels.

Results

Conclusion