Abstract
This study aimed to formulate and characterize the drug-release, physicochemical, and biological properties of doxycycline (DOX)-loaded mesoporous nanosilica (MNS) within experimental resin primers and to investigate the resin-dentin interfacial structure, properties, and performance in terms of microtensile bond strength (uTBS) under different clinically simulating biodegradation/aging conditions using ex-vivo teeth models for a duration of 12 months.
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