Abstract

More evidence indicates image detection and activation of a leading role in bone repair of the β-catenin signaling pathway. However, the role of β-catenin signaling in fracture healing at the remodeling stage is currently unknown. In this study, β-catenin was removed in mice at different levels of activation or at a later stage of fracture healing. The impact on healing quality was examined based on IoT. Loss of bone remodeling and β-catenin interference is increased β-catenin bone resorption and decreased bone formation, and significantly reduced compared to wild-type mice, as evidenced by bone strength. The constitutive activation of β-catenin is significant, increasing bone mass and delaying the bone remodeling process, resulting in slightly impaired β-catenin bone strength. Mutual studies have found that postpartum mice develop articular cartilage with too little strategy using (Cre) Col2 and collagen type 2) COL2-cree, β-catenin growth. Plate collapse was caused by conditional ablation and bone severe volume loss is based on image detection analysis. In summary, these data provide evidence that β-catenin signaling plays an important and unique role in the growth plate and articular cartilage. Misregulation of the leads of this signaling pathway due to various structural and functional changes in the two cartilage structures after childbirth.

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