Abstract
Presented here is a novel Ca(II) compound, that is, {[(CH 3 ) 2 NH 2 ] 2 [Ca 5 (L) 4 (DMF) 4 ]} n ( 1 , H 3 L = 4,4′,4″-ticarboxytriphenylamine), with rare pentanuclear [Ca 5 (COO) 8 ] clusters as building subunits. The L 3− ligands connected all pentanuclear [Ca 5 (COO) 8 ] clusters into a 3-dimensional anionic skeleton that was balanced via dimethylamine cations. Furthermore, the thermal behavior and compound's luminescent performance were also examined. For the treatment of atherosclerosis, the enzyme linked immunosorbent assay (ELISA) detection assay was implemented for the exploration of the fresh compound's influence against the inflammatory cytokines levels released into plasma. After that, the real time reverse transcription-polymerase chain reaction (RT-PCR) was finished and the nuclear factor kappa-B (NF-κb) signaling pathway activation in vascular endothelial cells was tested. • A novel Ca(II) compound was prepared. • The thermal and luminescent properties were examined. • Its treatment activity of atherosclerosis was studied.
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