Abstract

Abstract The germline gene-editing field has several detailed preclinical research guidelines but lacks concise and plain-language ethics statements on ultimate clinical uses. The general public deserves a clear vision of the future to gauge the field's ultimate intentions and have meaningful input and discussion about its progress. We propose the identification of a core set of fundamental human values to frame, guide, and restrict clinical applications that communities around the world can share and localize based on religious beliefs, culture, and public-health challenges.

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