Abstract
In this paper, a novel mercury-free electrochemical probe was constructed for the trace determination of octamethylcyclotetrasiloxane (D4) in some biological fluids by adsorptive stripping voltammetry. The platform is based on the adsorptive accumulation of Ni(II) onto a carbon paste electrode modified with citrate stabilized Fe3O4 (Cit-Fe3O4) and dimethylglyoxime (DMG). It was shown that trace levels of D4 enhance the electrochemical adsorptive stripping signal of Ni(II) on the electrode platform. It was shown that electrochemical signals are proportional to concentrations of D4. The supporting electrolyte, pH and instrumental parameters associated with the electrode response, including scan rate, accumulation potential and deposition time were optimized. The electrode platform demonstrated well resolved, reproducible peaks, with relative standard deviation (RSD) of 3.8% and detection limit (3Sb/m) of 27.0 ng/mL. The sensor exhibited good D4 detection and quantification in human blood plasma and urine samples.
Highlights
As low molecular weight (LMW) compounds, siloxane derivatives play a vital role in human life
The characteristic peak at 578 cm−1 is related to the vibration of Fe–O bond which confirms the magnetic phase of nanoparticles
The microstructure of Cit-Fe3O4 nanocrystal was characterized by the x-ray diffraction (XRD) technique
Summary
As low molecular weight (LMW) compounds, siloxane derivatives play a vital role in human life.
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