RETRACTED ARTICLE: A porous Er(III)–organic framework as a highly efficient catalyst for chemical fixation of CO2 and treatment activity on senile deafness via inducing the cochlear hair cell apoptosis

Abstract

A microporous Er(III)-based metal–organic framework (MOF), whose chemical formula can be written as {[Er(TCPB)(H2O)]·dioxane·0.5H2O}n, has been formed from the tripodal ligand 1,3,5-tris(4-carbonylphenyloxy)benzene (H3TCPB) by solvothermal synthesis and determined by the single crystal X-ray diffraction and the elemental analysis. With the aid of microporous framework and abundant catalytic sites of open Er(III) sites, the activated 1 is a special catalyst for the synthesis of cyclic carbonates from carbon dioxide and epoxy compounds under the cocatalyst TBAB and gently solvent-less conditions. The treatment activity of the compound on the senile deafness, as well as the influence of the compound on the cochlear hair cell death was explored. Firstly, the cell apoptosis of the cochlear hair cells was estimated via CCK-8 assay. Next, the activation of the caspase-3,8 was evaluated with western blot.