Retracted: A new Zn(II) coordination polymer: Selective detection of Fe3+ and treatment activity of the exercise induced traumatic osteoarthritis by reducing reactive oxygen species production

Abstract

AbstractThrough utilizing the fluorescent ligand of tris(4‐(triazol‐1‐yl)phenyl)amine, an innovative Zn(II)‐based coordination polymer formulated as {[Zn2(μ‐OH2)(TTPA)(DTDN)2·DMF]·H2O}n (1, DTDN = 6,6′‐dithiodinicotinate and TTPA = tris(4‐(1H‐1,2,4‐triazol‐1‐yl)phenyl)amine) has been successfully prepared by using the H2DTDN as the auxiliary ligand under the solvothermal reaction conditions and structurally characterized. According to the results of fluorescence spectrum analysis, complex 1 has high sensitivity and selectivity for Fe3+ ion. It can effectively detect Fe3+, the linear range is from 0 to 1,000 μM, and the detection limit of Fe3+ is 8.65 nM. Its treatment activity against exercise induced traumatic osteoarthritis was estimated and its detail mechanism was also investigated in meantime. First, the detection assay of reactive oxygen species (ROS) was implemented for the assessment of the ROS levels produced in the articular soft tissue after compound treatment. Besides, the reverse transcription‐polymerase chain reaction (RT‐PCR) was also conducted and the genes relative expression related with ROS production was measured after compound exposure.