Abstract

AbstractA novel coordination polymer based on Co(II) has been generated utilizing the 4,4′,4″‐phosphanetriyltribenzoic acid (H3tpp) as the tritopic connector in the existence of a second N‐donor ligand 3,3′‐bipyridine (3,3′‐bpy) under the solvothermal reaction conditions, and its chemical formula is [Co3(tpp)2(3,3′‐bpy)]·7DMF (1). Moreover, under ultraviolet irradiation, complex 1 has high photocatalytic activities for methylene blue degradation, and its photodegradation performance does not show much reduction after three cycles of experiments. Furthermore, the compound's biological activity against the mania was assessed, and the protentional mechanism was discussed. First, the neuroregulin1 content in the hippocampus was detected via enzyme‐linked immunosorbent assay to evaluate the compound's treatment activity on mania. Then, the ErbB4 relative expression levels were detected using real‐time reverse transcription‐polymerase chain reaction. The carboxyl groups have been confirmed to be responsible for all the binding interactions formed by molecular docking simulation.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.