Abstract
In January, 2019, a 37-year-old, White man presented to Saint-Etienne University Hospital (France) with relapsed Hodgkin lymphoma. A PET-CT scan showed hypermetabolic adenomegaly above and below the diaphragm, without visceral or bone involvement. Two cycles of intravenous chemotherapy (gemcitabine 800 mg/m2, vinorelbine 15 mg/m2, and pegylated liposomal doxorubicin 10 mg/m2 on days 1 and 8 every 21 days) resulted in a complete metabolic response in March, 2019. Consolidation consisted of double umbilical cord blood transplantation (dUCBT; total nucleated cells 15·4 × 107 cells per kg and 19·1 × 107 cells per kg for each cord, CD34+ cells 6·5 × 105 cells per kg and 7·9 × 105 cells per kg) after an intravenous conditioning regimen (thiotepa 5·0 mg/kg, busulfan 3·2 mg/kg, fludarabine 40 mg/m2, thymoglobulin 5·0 mg/kg).
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