Abstract
Retinol esterification was demonstrated in vivo and in vitro in lamb kidney. Retinol labeled with hydrogen-3 injected into the renal artery of lambs appeared in the labeled retinyl ester fraction in the renal vein. Degree of tracer incorporation into retinyl esters increased with vitamin A intake. In homogenates, activity was concentrated in microsomes and enhanced fourfold by addition of adenosine 5’-triphosphate and coenzyme A to the incubation mixture. These findings suggest that the esterification is a function of fatty acyl coenzyme A:retinol acyl transferase. Renal esterification may play a role in retinol homeostasis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
