Retinoblastoma in Late Childhood

B Badhu,R P Sah,S Kumar,S P Sah

doi:10.31729/jnma.844

Abstract

Retinoblastoma, the commonest intra-ocular tumor of childhood, is rare after the ageof 5 years. We report a case of retinoblastoma in a 10 year-old boy, who presentedwith a fungating proptosed tender mass involving the entire left eye and the orbit. Aclinical diagnosis of retinoblastoma was made. Exenteration of the left orbit was done.Histopathology revealed well-differentiated retinoblastoma with the involvement ofoptic nerve section. CSF and bone marrow aspirates did not show any malignantcells. This paper highlights the delayed presentation of retinoblastoma in late childhoodand discusses the treatment modalities of orbital retinoblastoma.Though retinoblastoma in late childhood is uncommon, it should be considered in thedifferential diagnosis of leukocoria and a fungating proptosed mass.Key Words: Retinoblastoma, late childhood, fungating proptosed mass.

Highlights

Retinoblastoma, the commonest intra-ocular tumour in childhood, is diagnosed before 5 years of age in 90% of cases.[1,2] It has, been reported in adults[3,4] even in a 74-year-old man.[5]
We found a case of retinoblastoma presenting as a proptosed fungating orbital mass in a 10-year-old boy at B.P.Koirala Institute of Health Sciences, Dharan, Nepal
Sah, Kumar, Dulal, Sah : Retinoblastoma in late childhood painful rapidly growing foul smelling mass involving his left eye for three months

Summary

INTRODUCTION

Retinoblastoma, the commonest intra-ocular tumour in childhood, is diagnosed before 5 years of age in 90% of cases.[1,2] It has, been reported in adults[3,4] even in a 74-year-old man.[5]. Sah, Kumar, Dulal, Sah : Retinoblastoma in late childhood painful rapidly growing foul smelling mass involving his left eye for three months. It was preceded by the presence of a white pupillary reflex associated with diminution of vision in the affected eye for six months. Examination revealed a fungating proptosed tender mass of firm consistency with irregular surface and necrotic areas involving the entire left eye and orbit (Fig. 1). CT scan of the orbit showed a mass involving the entire eyeball with areas of calcification as well as the involvement of optic nerve and periorbital tissue.

DISCUSSION

Findings

CONCLUSION

Transactions of the American Ophthalmologic