Abstract
BackgroundTo report a rare case of granular cell tumor invading the retina.Case presentationA 56-year-old female complained of blurred vision for 2 weeks in her left eye. An irregular-shaped retinal mass in the inferonasal and extending to the optic disc accompanied by dense exudation and extensive serous retinal detachment was observed. Several intravitreal bevacizumab injections were ineffective for stabilizing retinal exudation and intraocular pressure (IOP). Vitrectomy was performed to re-attach the retina and obtain a tumor biopsy specimen. Histopathological analysis revealed that the intraocular mass was a granular cell tumor. Immunohistochemical studies demonstrated that the tumor was positive for S100 and CD68, focal positive for neurofilaments, but negative for ERG and HMB-45. Local recurrence and distant metastasis were not found, but visual acuity had worsened to no light perception at the last visit due to uncontrolled intraocular pressure and retinal exudation after the surgery.ConclusionsGranular cell tumor is a rare benign neoplasm, but it can lead to devastating visual loss if it invades the retina adjacent to the optic nerve head.
Highlights
To report a rare case of granular cell tumor invading the retina.Case presentation: A 56-year-old female complained of blurred vision for 2 weeks in her left eye
Granular cell tumor is a rare benign neoplasm, but it can lead to devastating visual loss if it invades the retina adjacent to the optic nerve head
Granular cell tumor (GCT), known as Abrikossoff tumor, is a rare soft-tissue neoplasm thought to originate from Schwann cells [1]
Summary
To report a rare case of granular cell tumor invading the retina.Case presentation: A 56-year-old female complained of blurred vision for 2 weeks in her left eye. Conclusions: Granular cell tumor is a rare benign neoplasm, but it can lead to devastating visual loss if it invades the retina adjacent to the optic nerve head. We describe a rare case of a retinal mass surgically excised and histologically diagnosed as a GCT.
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