“Retinal anlage tumor of infancy”: Reportof a case occurring in the anterior fontanel

Abstract

A benign, rare, melanotic tumor, occurring in infants under 12 months of age, hasbeen variously called "retinal anlage tumor", "melanotic progonoma" and "melanotic adamantinoma." Approximately 40 cases have been documented, the majority occurring in the maxilla and mandible. In only a few cases, the tumor was extrafacial. In the present case, the growth occurred in the anterior fontanel. Grossly the tumor was pigmented, and microscopically it was composed of fibrous tissue, cuboidal cells containing melanin pigment, and small cells resembling neuroblasts.