Abstract
An autopsy case of rapidly growing reticulum cell sarcoma of the breast with terminal leukemic manifestation and wide disseminations, including bilateral ovarian involvement, is reported. Metastatic tumors in the lymph nodes and in the right chest wall were sensitive for bleomycin, the combined chemotherapies with Mitomycin C, 5‐FU, and Cytosine Arabinoside, and with Vincristine, Endoxan, 6MP, and prednisolone, and radiation therapy by Lineac, but only a short survival was finally obtained. The histology of the tumors is characterized by single cell pattern with medium sized polygonal cells. Investment of reticular fibrils by the cytoplasm of the tumor cells is revealed by electron microscopy.
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