Abstract
Objective To investigate the variation and clinical significance of reticulocyte parameters before and after the chemotherapy for malignant tumor.Methods 36 patients,admitted to our hospital from January to December,2013,needing chemotherapy,were selected as study objects.Sysmex XT4000i automated hematology analyzer was used to observe the change of reticulocyte parameters before and after the chemotherapy.Results The WBC values were significantly lower on day 7 after the chemotherapy and decreased to a minimum on day 14,with a statistical difference (P ＜ 0.05).The WBC values bcgan to rise on day 21.The reticulocyte parameters and immature reticulocyte index decreased to a minimum on day 7,with statistical differences (P ＜ 0.05).The reticulocyte parameters and immature reticulocyte index began to rise on day 14,and recovered to the levcl before chemotherapy on day 21.Conclusions Reticulocyte parameters is a sensitive indicator for evaluating the inhibition of bone marrow function before and after the chemotherapy and is worth being clinically generalized. Key words: Malignant tumor; Reticulocyte parameters ; Chemotherapy
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