Abstract
Eight animals were stimulated within the dorsolateral midbrain reticular formation while performing in situations designed to be sensitive to variations in drive level. Amount of gross activity, fine activity, exploration, and bar presses to obtain food and avoid shock was suppressed as an increasing function of stimulating current from 10 to 125 μamp. Electrocortical activation was seen in all animals with reticular stimulation, and grossly observable alerting, fear and forced motor reactions were described. The reward value of stimulation was tested in the majority of animals, and an increasing tendency toward escape of the central stimulus was seen with increasing amperage. It is concluded that direct midbrain reticular excitation does not produce a corresponding increase in drive or motivational level that would be evidenced as facilitation of a wide variety of activities.
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