Abstract
Rethinking Alzheimer’s Disease
Highlights
Alzheimer’s disease (AD) begins insidiously, usually with memory difficulties, many years before the patient has a cognitive and functional decline compatible with the diagnosis of dementia
It is often difficult to appreciate the memory complaints in the initial phase of AD, because healthy people frequently report an unfavorable opinion about their own memory, and there is a slight decline in objective memory performance in the aging process (Mendes et al, 2008)
The nosologic concept of mild cognitive impairment (MCI) has been very useful to establish the probability of progression to dementia and promote an adequate followup in these patients
Summary
AD begins insidiously, usually with memory difficulties, many years before the patient has a cognitive and functional decline compatible with the diagnosis of dementia. The nosologic concept of MCI has been very useful to establish the probability of progression to dementia and promote an adequate followup in these patients.
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