Abstract
The use of retention time locking (RTL) in the development of unified procedures for the detection and quantitative determination of drugs in biological fluids was considered. With consideration for the use of RTL, a chromatographic procedure with flame-ionization and mass-selective detection was developed for the detection and quantitative determination of opiates and their synthetic analogs; phenylalkylamine derivatives; cocaine; ketamine; and other narcotic drugs, their derivatives, and metabolites in urine. The analytical ranges for chromatography–mass spectrometry were 0.05–1000 and 0.005–1000 μg/mL under the conditions of total ion current (TIC) scanning and selected ion monitoring (SIM), respectively. With flame-ionization detection (GC–FID), the analytical range was 0.5–1000 μg/mL.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
