Abstract

In this work, octadecyl acrylate (ODA) having a reactive group at one side of the terminal groups were synthesized and evaluated using the extract products in oriental medicine formulations by high-performance liquid chromatography (HPLC). By elemental analysis as well as IR and NMR spectroscopy, the average degree of polymerization of ODA-modified silicas were determined to be 19. Using acetonitrile–water mixtures as the eluent, ginsenosides Rb1 and Rg1 in commercial Panax Ginseng or Red Ginseng were separated on ODA-modified silicas, but with different degrees of resolution comparing with ODS-modified silicas.

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