Abstract
While hemorrhagic shock might be the result of various conditions, hemorrhage control and resuscitation are the corner stone of patient management. Hemorrhage control can prove challenging in both the acute care and surgical settings, especially in the abdomen, where no direct pressure can be applied onto the source of bleeding. Resuscitative endovascular balloon occlusion of the aorta (REBOA) has emerged as a promising replacement to resuscitative thoracotomy (RT) for the management of non-compressible torso hemorrhage in human trauma patients. By inflating a balloon at specific levels (or zones) of the aorta to interrupt blood flow, hemorrhage below the level of the balloon can be controlled. While REBOA allows for hemorrhage control and augmentation of blood pressure cranial to the balloon, it also exposes caudal tissue beds to ischemia and the whole body to reperfusion injury. We aim to introduce the advantages of REBOA while reviewing known limitations. This review outlines a step-by-step approach to REBOA implementation, and discusses common challenges observed both in human patients and during translational large animal studies. Currently accepted and debated indications for REBOA in humans are discussed. Finally, we review possible applications for veterinary patients and how REBOA has the potential to be translated into clinical veterinary practice.
Highlights
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an endovascular hemorrhage control intervention that was first described in the Korean war [1]
The practice of REBOA has benefited from significant advances mostly aimed at reducing ischemia-reperfusion injury
While there is no published study reporting its clinical use in veterinary patients to date, REBOA might have application in veterinary practice
Summary
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an endovascular hemorrhage control intervention that was first described in the Korean war [1]. REBOA has recently re-gained popularity as an alternative to resuscitative thoracotomy (RT, thoracotomy and aortic crossclamping) in trauma patients [2,3,4,5,6,7,8]. With REBOA, aortic blood flow can be controlled via the insertion of a balloon-tipped catheter inside the aorta through the common femoral artery. REBOA allows for hemorrhage control via cessation of aortic flow across the balloon thereby promoting clot formation and hemodynamic stabilization. The development of low-profile REBOA catheters [11] as well as recent translational and clinical research have contributed to significant advancements in REBOA implementation. This review will describe the implementation of several REBOA strategies (complete, intermittent, and partial occlusion), discuss its clinical benefits and limitations, and describe possible applications in veterinary medicine
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