Abstract
Postoperative recurrence (POR) after an ileocolonic resection with ileocolonic anastomosis is frequently encountered in patients with Crohn's disease. The 8 th Scientific Workshop of ECCO reviewed the available evidence on pathophysiology and risk factors for POR. In this manuscript, we will discuss published data on the role of the microbiome, the mesentery, the immune system, and the genetic background. In addition to the investigation of causative mechanisms of POR, identification of risk factors is essential to tailor preventive strategies. Potential clinical, surgical and histological risk factors are presented along with their limitations. Emphasis is placed on unanswered research questions, guiding prevention of POR based on individual patient profiles.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
