Abstract
The surgical correction of ventricular septal defects can be accomplished today by teams experienced in extracorporeal perfusion technics with a minimum of risk and a maximum of effectiveness. There has been no operative mortality during the past two years in the series reported, regardless of the degree of pulmonary hypertension. With this degree of success it is believed that patients with significant shunt flows (40 per cent or more) should have the shunts closed without waiting for the development of enlarged hearts, increased pulmonary vascularity and pulmonary hypertension. Operative intervention is delayed in infants less than one year of age or less than 20 pounds in weight because of the increased risk.
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