Abstract
In 2015 a study to evaluate the effectiveness of the drug "Mildronate" was carried out in the Federal State Budgetary Institution at the A.I. Burnazyan Federal Medical and Biological Center of the Russian Federal Medical and Biological Agency. The study involved 20 representatives of skiing sports (biathlon, cross-country skiing, cross-country skiing) (10 men, 10 women), mean age 20.1 ± 0.6 years. The level of sportsmanship was not lower than the first adult grade. Five men and five women took placebo, and five men and five women received Mildronate. Allocation into groups was carried out according to the maximum time of the exercise test in the ergospirometric study (ski-treadmill traverse). The study was built from the position of activity approach, reflecting the basic characteristics of the athlete's activity: physical and psychological readiness to achieve the best result (imitation of competitive activity). Specific load testing on skis and objective diagnostics of the psycho-emotional state was carried out. Comparative assessment of the indicators was carried out on the 7th and 15th days of the study in relation to the background. According to the subjective evaluation of the drug's effect, the greatest number of positive changes in the state were noted by participants who took placebo. For 7 out of 10 people positive dynamics in the subjective state was observed (mood, sleep and general well-being improved, physical performance increased, training results increased). The placebo effect of taking the drug on the psychophysiological state of the persons professionally engaged in sports was detected. This can be explained by the formation of a stable notion that the level of professional skill depends on the use of pharmacological agents. Received materials indicate a pronounced psychotherapeutic effect of "Mildronat" on the functional and adaptive reserves of healthy athletes, ensuring the preservation of high-performance capacity. Expert evaluation of new technologies of sports medicine and drugs, affecting physical performance should necessarily include determination of functional readiness dynamics, including placebo-controlled comparative studies and objective diagnostics of psycho-emotional state.
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