Results of Histological Examination of the Placenta in Preterm Birth Among Residents of the Kaliningrad Region With Hereditary Maladaptation of Hemostasis

Abstract

In modern obstetrics, the problem of premature birth is very relevant. Despite the active development of medical technologies, the number of preterm births stably remains at the level of 5-10% of the total number of births, and recurrent miscarriage reaches 20%. As is known, one of the causes of preterm birth and recurrent miscarriage is the carriage of genes associated with thrombophilia. We are studying the effect of thrombogenic allelic polymorphisms on the course of pregnancy and the outcome of childbirth in the population of the Kaliningrad region. One of the points of our research is devoted to the description of structural changes in the placenta during preterm labor in women with hereditary maladaptation of hemostasis.