Results of Coronary Artery Bypass Surgery Combined With Endarterectomy and Reconstruction of Anterior Descending Artery in Patients With Diabetes Mellitus

Abstract

To assess results of coronary artery bypass surgery combined with endarterectomy (EAE) in patients with ischemic heart disease (IHD) and diabetes mellitus (DM), and impact of DM on clinical outcomes. We recruited in this study 152 patients with IHD (43 with and 109 without DM) subjected to coronary artery bypass surgery with EAE from anterior descending artery (ADA) between 2003 and 2010. Forty three patients had concomitant DM (main group) 109 - had not (control group). Mean age was 57+/-18 and 60+/-19 years, portion of patients with class III-IV angina - 71.1 and 73.3%, with history of myocardial infarction - 74.4 and 68.8%, in main and control group, respectively (p>0.05). In hospital mortality was 4.6 and 3.6% in main and control group, respectively. Number of patients examined in remote period was 127 (87.6%). Mean follow-up was 4.5+/-1.2 years. Survival was 90.7 and 100% (p>0.05). Graft angiography was performed in 12 and 43 patients (27.9 and 39.4%) with portions of patent arterial conduits 91.6 and 100%, patent venous conduits 90.0 and 90.3% in main and control group, respectively. Under conditions of strict control of glycemia coronary artery bypass surgery with EAE from ADA in IHD patients with DM is associated with acceptable hospital mortality and survival, moderate risk of remote cardiovascular complications, and satisfactory patency of conduits.