Abstract
100 patients undergoing colorectal surgery were entered into a prospective randomised double-blind trial of the collagenase inhibitor aprotinin (Trasylol). Post-operative assessment of the integrity of the anastomoses was performed and the overall radiological leakage rate was 22% for the aprotinin group and 35% for the placebo group. The overall clinical leakage rate was 8 and 15 % for aprotinin and placebo, respectively. This reduction in the leakage rates may be of clinical importance and further studies are therefore warranted.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
